18.417 Introduction to Computational Molecular Biology

As taught in: Fall 2004

A DNA helix rendered in ASCII art.

A DNA helix rendered in ASCII art. (Image courtesy of Ramona Saldamando. Used with permission.)




Ross Lippert

Course Features

Course Description

This course introduces the basic computational methods used to understand the cell on a molecular level. It covers subjects such as the sequence alignment algorithms: dynamic programming, hashing, suffix trees, and Gibbs sampling. Furthermore, it focuses on computational approaches to: genetic and physical mapping; genome sequencing, assembly, and annotation; RNA expression and secondary structure; protein structure and folding; and molecular interactions and dynamics.