18.417 Introduction to Computational Molecular Biology

As taught in: Fall 2004

A DNA helix rendered in ASCII art.

A DNA helix rendered in ASCII art. (Image courtesy of Ramona Saldamando. Used with permission.)

Level:

Graduate

Instructors:

Ross Lippert

Course Features

Course Description

This course introduces the basic computational methods used to understand the cell on a molecular level. It covers subjects such as the sequence alignment algorithms: dynamic programming, hashing, suffix trees, and Gibbs sampling. Furthermore, it focuses on computational approaches to: genetic and physical mapping; genome sequencing, assembly, and annotation; RNA expression and secondary structure; protein structure and folding; and molecular interactions and dynamics.