5.451 Chemistry of Biomolecules I

As taught in: Fall 2005

Image showing the multi-colored coils of shikimate kinase.

Crystal structure of shikimate kinase. (Image courtesy of the RCSB PDB. PDB ID: 1VIA. Badger, J., et al. "Structural analysis of a set of proteins resulting from a bacterial genomics project." Proteins 60 (2005): 787-796.)

Level:

Graduate

Instructors:

Prof. Sarah O’Connor

Course Features

Course Description

5.451 is a half-semester introduction to natural product biosynthetic pathways. The course covers the assembly of complex polyketide, peptide, terpene and alkaloid structures. Discussion topics include chemical and biochemical strategies used to elucidate natural product pathways.